Hello everyone, in today's micro-lesson, we will be discussing the pharmacokinetics of drugs. Pharmacokinetics is the study of how the body absorbs, distributes, metabolizes, and excretes drugs. Firstly, let's talk about absorption. This is the process by which a drug enters the bloodstream from its site of administration. Factors such as the route of administration, the drug's chemical properties, and the presence of food can affect the rate and extent of absorption. Next, distribution refers to how a drug is transported throughout the body. Factors like blood flow to various tissues, protein binding, and the drug's lipid solubility can influence how widely a drug is distributed. Metabolism, or biotransformation, involves the body's process of breaking down drugs into molecules that are easier to eliminate. The liver is the primary organ responsible for drug metabolism, through enzymes like the Cytochrome P450 system. Lastly, drug excretion is the removal of drugs and their metabolites from the body, primarily through the kidneys in the form of urine. Some drugs may also be excreted through the feces, sweat, or breath. Understanding pharmacokinetics is crucial in determining the appropriate dosage, dosing frequency, and potential interactions of drugs in the body. Thank you for listening, and I hope this micro-lesson has expanded your knowledge on this important aspect of pharmacology.