Menthol, a naturally occurring organic compound extracted from mint plants, is known for its cooling and aromatic properties. Due to its unique physical and chemical characteristics, menthol has found extensive applications across various industries, including pharmaceuticals, food, cosmetics, fragrances, and agriculture. This report explores the primary applications of menthol, its mechanisms of action, and specific use cases in different fields.1. Physical and Chemical Properties of MentholMenthol is a white or colorless crystalline substance with a strong minty odor and cooling sensation. Its molecular formula is C10H20O, and it has a molecular weight of 156.27 g/mol. Menthol has a melting point of 38°C-39°C and a boiling point of 212°C-216°C. It is soluble in alcohol and ether but insoluble in water, making it versatile for various applications across different media.2. Major Application Areas of Menthol2.1 Pharmaceutical IndustryMenthol is widely used in the pharmaceutical industry for its therapeutic properties, including:2.1.1 Analgesic and Anti-itchMenthol is commonly used to relieve minor pain, itching, and inflammation. It works by activating cold-sensitive receptors such as TRPM8, creating a cooling sensation that helps alleviate pain and itching. Menthol is a common ingredient in topical creams, sprays, and patches.As a food additive, menthol is primarily used for flavoring and enhancing the sensory experience of food products. It is widely used in chewing gum, candies, beverages, and ice creams, providing a refreshing taste and aroma.