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Are you feeling tightness in your chest? Are you coughing a lot, especially at night? That must be asthma!

Prince Igor
2024-04-14 16:40:39
Asthma is a condition marked by airway inflammation and reversible bronchospasm. Medications used for treatment include bronchodilators, which relax smooth muscles, and anti-inflammatory drugs. Bronchodilators includeAre you feeling tightness in your chest? Are you coughing a lot, especially at night? That must be asthma!Bronchodilators include β2-selective agonists, muscarinic antagonists, methylxanthines, and leukotriene receptor blockers. Asthma is a condition marked by airway inflammation and reversible bronchospasm. Medications used for treatment include bronchodilators, which relax smooth muscles, and anti-inflammatory drugs. Bronchodilators include β2-selective agonists, muscarinic antagonists, methylxanthines, and leukotriene receptor blockers.Now, let's take a closer look at what happens inside the lungs when someone has asthma.In asthma, triggers such as allergens or irritants can cause a chain reaction in the airways. This reaction involves special cells called mast cells, which release mediators like leukotrienes LTC4 and LTD4, as well as chemotactic factor LTB4. These mediators lead to bronchoconstriction, where the muscles around the airways tighten, making breathing difficult. This process also attracts inflammatory cells like eosinophils, neutrophils, and lymphocytes, which further contribute to inflammation and airway damage. This cycle of inflammation and bronchoconstriction results in the symptoms of asthma, including wheezing, coughing, and shortness of breath. Treatment focuses on reducing inflammation and preventing bronchoconstriction to manage symptoms and improve lung function.So? What are the strategies of asthma therapy?A key aspect of managing asthma is the timely and effective treatment of acute bronchospasm. This is typically achieved using bronchodilators, which are often referred to as reliever drugs. There are several types of bronchodilators available for this purpose, including beta2 agonists, muscarinic antagonists, and theophylline and its derivatives. In addition to treating acute symptoms, long-term management of asthma also involves controlling the underlying inflammatory process in the airways. This is where controller drugs come into play. Corticosteroids are considered the most important anti-inflammatory drugs for the treatment of chronic asthma. They help reduce airway inflammation and prevent asthma symptoms.

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